Early nocturnal meal skipping alters the peripheral clock and increases lipogenesis in mice
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چکیده
منابع مشابه
Early nocturnal meal skipping alters the peripheral clock and increases lipogenesis in mice
UNLABELLED BACKGROUND In humans, skipping meals, especially breakfast, has been associated with obesity and other related syndromes. Recent studies in rodents suggest that fasting and feeding times are potential factors that affect the peripheral circadian clocks and metabolism. However, the link between fasting and obesity in rodents has yet to be fully demonstrated. METHOD We conducted e...
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Circadian rhythms in mammals are regulated by a system of circadian oscillators that includes a light-entrainable pacemaker in the suprachiasmatic nucleus (SCN) and food-entrainable oscillators (FEOs) elsewhere in the brain and body. In nocturnal rodents, the SCN promotes sleep in the day and wake at night, while FEOs promote an active state in anticipation of a predictable daily meal. For noct...
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The mammalian target of rapamycin complex 2 (mTORC2) contains the essential protein RICTOR and is activated by growth factors. mTORC2 in adipose tissue contributes to the regulation of glucose and lipid metabolism. In the perivascular adipose tissue, mTORC2 ensures normal vascular reactivity by controlling expression of inflammatory molecules. To assess whether RICTOR/mTORC2 contributes to bloo...
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The peripheral circadian clock is entrained by factors in the external environment such as scheduled feeding, exercise, and mental and physical stresses. In addition, recent studies in mice demonstrated that some food components have the potential to control the peripheral circadian clock during scheduled feeding, although information about these components remains limited. l-Ornithine is a typ...
متن کاملCorrelates of meal skipping in young adults: a systematic review
BACKGROUND Meal skipping rates may be highest during young adulthood, a period of transition and development. Although these dietary behaviours may increase future risk of chronic disease, limited research has investigated correlates of meal skipping in young adults. METHODS A systematic literature search was conducted to identify studies that investigated correlates of meal skipping behaviou...
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ژورنال
عنوان ژورنال: Nutrition & Metabolism
سال: 2012
ISSN: 1743-7075
DOI: 10.1186/1743-7075-9-78